Omega 3 has many known benefits and acts in particular on the nervous system, the brain and vision .
More recently, DHA and EPA have been the subject of several studies which have highlighted their impact on the immune system.
The proven benefits of Omega 3 (DHA and EPA)
It is now fully accepted that Omega 3 fatty acids are essential for the development, maintenance and functioning of the retina, brain and nervous system , starting from the earliest stages of intrauterine life.
In the cardiovascular field , scientific data clearly shows a positive role of Omega 3 for:
- Regulation and reduction of blood pressure in people with high blood pressure;
- Reducing the amount of triglycerides in the blood, lipids which, in excess, lead to the development of heart disease;
- A reduction in cardiovascular morbidity and mortality in people with pathologies in this area,
In brain function, EPA and DHA, the two most functional forms of Omega 3, play an active role and also intervene during aging.
They probably have a positive effect on maintaining mental health (lower prevalence of depression and dementia including Alzheimer's disease), and studies are underway to confirm these properties.
For vision: DHA and EPA are also thought to be involved in the prevention of age-related macular degeneration (AMD). Indeed, a deficiency in these fatty acids appears to increase the risk of AMD.
In France, ANSES has validated all of the health claims mentioned above.
The new important properties of Omega 3 on immunity
Several recent studies have highlighted the role of Omega 3 on cancer and immunity.
DHA and reduction of cancer tumors
As we detailed in a previous article, the team led by oncologist Olivier Feron at the IREC of the University of Louvain has highlighted the mechanisms of action of DHA which reduce the progression of cancerous tumors .
This considerable advance in the field of nutrition and health is obviously the subject of new studies, currently underway, to confirm and clarify the conditions of action of DHA in situations of tumor acidosis and the resulting preventive properties.
The action of Omega 3 on general immunity
The COVID pandemic has relaunched a number of studies and in-depth studies on the mechanisms of immunity, including those of so-called "general" immunity which concerns all of the body's reactions to resist any type of microbial attack.
Our immune defenses implement multiple and complex mechanisms that must work in cascade and in harmony to be effective.
The first levels of internal resistance of the organism are constituted by the lymphocyte cells (T when produced by the thymus or B 'bones' by the bone marrow).
Their excitation in response to a microbial attack always results in local inflammation of the directly affected tissues (e.g. the throat in the case of many airborne pathologies). These inflammations maintain the consequences of the pathology.
Recent experimental results all converge towards a positive role of EPA and DHA in reducing inflammatory phenomena resulting from microbial attacks . This is particularly the meaning of the conclusions of the work published in 2020 by Professors Dr. Oliver Werz of Friedrich Schiller University and Dr. Charles N. Serhan of Harvard Medical School.
In Sweden, Dr. Saray Gutierrez reached similar conclusions with a positive correlation between adequate intakes of EPA and DHA and reduced inflammatory reactions.
In England, Professor Philip Calder (Southampton Medical University) took a particular interest in children, studying:
- Their differences in sensitivity to food allergies,
- Their skin reactions (eczema),
- Their resistance to infectious diseases
It concludes that a good diet with regular intake of EPA and DHA, both in pregnant and breastfeeding women and in young children, significantly reduces the risk of allergies and improves their general resistance to infections.
Dietary intake of Omega 3 still insufficient despite its proven benefits
A new series of scientific findings obtained in different countries by independent teams has established proven links between regular intake of EPA and DHA and the proper functioning of the immune system, including in young children, and even a possible reduction in sensitivity to allergies.
More precise information is still lacking on the mechanisms of action of Omega 3 in these areas, but these positive observations have generally been obtained with daily doses in accordance with nutritional recommendations, i.e. for an adult, EPA and DHA intakes of 250 mg/day .
These benefits are added to the qualities of Omega 3 already recognized.
As mentioned above, basic Omega 3 (ALA) intake through rich vegetable oils (rapeseed, walnuts, etc.) in a proportion of around one tablespoon/day (10 g) allows the body to synthesize the EPA it needs, but only 10% of the necessary DHA (the transformation coefficient of ALA into DHA is only 1% while it is 10% for EPA).
Let us remember that the actual daily intake of Omega 3 by the French is on average only 1/3 of the minimum desirable levels (0.6g/day) which would be necessary to reach at least an acceptable EPA threshold and for DHA which is 10 times less synthesized by the body (transformation coefficient of 1% from basic Omega 3 ALA) the deficit is even more critical.
DHA supplementation is therefore the best way to ensure that these specific and important needs are met .
Omega-3 DHA in our Argalys supplements
To facilitate additional intake of Omega 3 DHA, we have developed our Omega 3 DHA formula , 100% plant-based, extracted from algae grown in France.
Each capsule provides a dose of 250 mg of DHA per capsule.
The use of algae grown in a controlled environment allows for optimal quality and production without impact on the marine ecosystem and without traces of heavy metals.
Bibliography:
- Effects of Omega-3 Fatty Acids on Immune Cells” “ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834330/
- https://pubmed.ncbi.nlm.nih.gov/32340216/
- https://pubmed.ncbi.nlm.nih.gov/23701554/
- https://www.anses.fr/fr/content/les-acides-gras-om%C3%A9ga-3