Melatonin

The beneficial effects of melatonin on sleep :

Melatonin, also known as the “sleep hormone” gets its nickname from its beneficial activity on falling asleep and regulating circadian cycles.

It helps to synchronize sleep cycles with the natural day/night cycle.

Its use will be thus recommended for :

• Reduce the time of falling asleep
• Reduce the effects of jet lag
• Promote relaxation
• Reduce insomnia disorders

Melatonin and jet lag:

This is the famous jet lag that travelers suffer from! During a trip, jet lag can disrupt our internal clock and melatonin production cycles. The result: it is difficult to fall asleep at the right time and fatigue is quickly felt.

To solve this problem, you can help your body find the right rhythm by encouraging you to fall asleep thanks to melatonin.
This is also the advantage of this little spray that will follow you everywhere you travel!

When should we take the food supplement Melatonin?

It is enough to take your Melatonin 30 minutes before going to bed.
After taking it, prepare yourself for the sleep phase, if possible without screens or lights.

How many sprays ?

This supplement is intended for adults. It is recommended to take 2 sprays per day.

Children: Not recommended
Adolescents: A favorable medical opinion is advised before taking the supplement

How to take the spray ?

Simply point the spray directly into your mouth.

Duration of a cure :

Each bottle contains 90 sprays that is 90 days of cure. Beyond that, if the symptoms persist, it is preferable to consult a sleep specialist.

Precautions to be respected :

To preserve out of the range of the children, with the shelter of heat and moisture.
To consume within the framework of a varied and balanced food, and of a healthy way of life. Do not exceed the recommended dosage. Do not give to children under 12 years old
Pregnant and breast-feeding women, as well as teenagers, people suffering from autoimmune diseases, epileptics or asthma sufferers, should consult a doctor before taking any supplements.

• Dry extract of poppy: 50 mg
• Honey: 20 mg
• Melatonin: 1,9 mg
• Vitamin B6: 0,7 mg

Our hair lives a long time (3 to 6 years) and is subjected to many repeated daily aggressions:

• Pollution
• Sunlight
• Drying

These aggressions put our hair to a severe test.

To protect them, it is possible to act through micronutrition with natural ingredients to give them a stronger constitution and better resistance over time.

Keratin and sebum: the basic components of our hair

Our hair is mainly made up (at 90%) of a specific protein: Keratin.

They are also protected by an oily film: Sebum. This is the source of “greasy hair” when it is excessive.

In the hair, keratin is present in several places:

• In the body of the hair shaft in the form of a spiral with exceptional mechanical properties. It is the quality of this spiral that determines the vitality and suppleness of the hair
• In the follicle (the root of the hair) in the form of scales that will later constitute the protective cuticle.

Keratin is a family of proteins composed of 18 amino acids, among which Methionine and Cystine (the sulfur amino acids) play a fundamental role in the helical structure of this molecule in the cortex (the body of the hair).

It is the proper maintenance of this fragile helix structure that gives hair its essential elasticity and resistance properties: a lack of methionine and cystine results in softer, more brittle hair.

It should be noted that Keratin is not soluble in water, but it does have the ability to partially retain water molecules (hence the difference in texture between wet and dry hair).

Sebum is an external oily film that plays an essential protective role for the hair.
It is secreted by the sebaceous glands at the base of the follicle, in the scalp. It is made up of a cocktail of unsaturated lipids, including

• • Linoleic acid (Omega 6) helps limit water loss from the hair, while having softening and nutritive qualities.
  • Gamma-linolenic acid (Omega 3), in addition to maintaining hair elasticity, has anti-inflammatory properties: it calms irritations.
  • Oleic acid (Omega 9) has nourishing qualities for the hair, making it softer and more supple, but also more radiant.

The other components of our hair

The other components of hair (a little less than 10%) are minerals.

Zinc and Selenium are particularly useful (as well as Iron) for the hair’s resistance and protection against oxidative stress.

Zinc is a good catalyst (gas pedal) for the synthesis of Keratin.

What about vitamins? Are they really useful for hair?

It is tempting to say that all vitamins play a positive role in hair and scalp health.

However, it is important to highlight vitamin B6 (pyridoxine) and Biotin (vitamin H or B8) which act directly as cofactors for the synthesis of Keratin.

Hair growth seems to be particularly improved with adequate blood levels of Biotin. On the other hand, a lack of Biotin is quickly noted in the greater fragility of the hair.

Hair loss: a very specific phenomenon

The life cycle of a hair lasts from 3 to 6 years on average and includes 3 distinct phases:

• The anagen phase or hair growth phase, at a rate of 0.3 mm/day and represents more than 90% of the total duration of the cycle;
• The catagen phase or resting phase of the hair before it falls out (duration: about one month)
• The telogen phase: this is the hair loss phase where the hair is progressively expelled from the hair bulb.

The processes of hair loss and hair growth are not directly linked: each hair that falls out is not systematically replaced.

The balance between the two phenomena depends on multiple internal and external factors, in which sex hormones play a major role.

The internal factors that influence hair loss are :

• On the one hand, genetics and age determine hair color, the number of hair cycles and the gradual slowing of hair growth.
• On the other hand, hormonal balance:

Female estrogens promote hair growth while male testosterone increases hair loss, especially its derivative DHT (Dihydrotestosterone). These hormonal variations explain for example:

• The increase in hair in pregnant women (increase in the production of estrogen) and their more important fall after childbirth because of the fall in the level of blood estrogen;
• The frequent baldness in men (androgenic alopecia) due to the action of DHT.

External factors that influence hair loss and regrowth are:

• A slight seasonal sensitivity also linked to hormonal variations;
• Micronutrition, which has a direct influence on the constitution of the hair and the vigor of its regrowth, as explained above.

But then, how to act against hair loss?

Unlike micronutrition, which allows for a real improvement in hair quality with a direct rational approach, the possibilities of minimizing the impact of DHT on hair loss are very indirect and without any guarantee of proven results.

Among the natural means that can be considered, Saw Palmetto extract seems to have positive effects.

Two scientific studies have shown a positive impact at the end of a few months of treatment in about 2/3 of the patients followed, but this approach requires confirmation with more concordant results.

Studies :

• Référence : Morganti P., Fabrizi G., James B., Bruno C. (1998). Effect of gelatin-cystine and Serenoa repens extract on free radicals level and hair growth. J Appl Cosmetol 16 : 57-64.
• Référence : Prager N., Bickett K., French N., Marcovici G. (2002). A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 8(2) : 143-52